New hemisynthetic manoyl oxide derivatives with antimicrobial activity.
نویسندگان
چکیده
The synthesis and antimicrobial activity of ten labdane-type diterpenes derived from ent-3-beta-hydroxy-13-epi-manoyl oxide (ribenol) is reported. The chloroethyl carbamidic ester 9 showed the strongest antimicrobial activity against all the tested gram (+), gram (-) bacteria and pathogenic fungi. Moreover, the glycoside 11 exhibited an interesting activity against the three tested fungi.
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عنوان ژورنال:
- Chemical & pharmaceutical bulletin
دوره 49 7 شماره
صفحات -
تاریخ انتشار 2001